Microtubules seem to be to blame for causing a variety of diseases. When they malfunction, the outcomes can be disastrous by causing problems such as Down's Syndrome. By exploring yeast cells, researchers have been able to identify the structure of microtubules and the protein responsible for creating them. These structures play a role in gamete structure, therefore affect the sex cells, which can lead to other diseases, including cancer.
http://www.medicaldaily.com/news/20120501/9727/cell-gametes-sex-cells-microtubules-downs-syndrome-cancer.htm
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